20150713

Yeah

I'd like to know the etiology of my MS too, but I doubt we'll get that answer in our lifetime; it certainly shouldn't dissuade us from trying.

It's in an article about mitochondria and the role they may play in MS development.

20150620

Oh Yeah

I saw someone post a SK meme that they were on tysabri for 5 years and relapse free.

In typical Murican manner, I am going to one-up you.


(I was on avonex for the year before tysabri, with a 3 month wash out period)

20150601

Murica!

Where the sick are seen as profitable (for the drug companies, at least)

Since introduction, the two MS drugs I've been on have seen their rates skyrocket.

the first drug I used, Avonex, has increased 381% since it's introduction.

The drug which I am now on, Tysabri, has increased by 101.5%.

Damn, it's a good thing I have good insurance...and my wife works at a hospital! Of course, that is how I found my MS.

And if these greedy drug companies weren't so profit driven, this wouldn't be a problem; but in Murica! it's all about how much you can make. And this is why Capitalism will be replaced and Murica! will be ousted as the World Reserve Currency eventually.

My favorite quotes of the article:
"Every time a new drug came onto the market, the price of all the drugs jumped"
"The standard economic principle that more choices will drive down prices doesn't always apply in the topsy-turvy world of drug economics, especially in the United States." (Emphasis mine]

Something is not right here.

20150505

Yesterday

Last night I was going to the bathrooom to take a leak. When I was standing there, I felt like I was going to pass-out; however, I had just started urinating after a very challenging start. Having accomplished starting going, I certainly didn't want to stop. I figured I could complete the stream and then lay down.

NOPE

I regained consciousness after I was sitting on my ass with my back against the wall.

Holy shyte.

Note to self, If I feel the urge to pass out, immediately lay down.

Don't complete the stream, don't think about trying to put it off. LAY THE FSCK DOWN!

Worst part of it all isn't that I passed out, but my ass hurts...really bad. I must've landed on the corner where the tile meets the floor. I'm in pain here, but I didn't want to take any pain management for fear of something being wrong. I won't be able to until tonight after the kids go to bed.

Oh, did I mention what I think caused it? I found a dent in the roof of my 15 day old 2015 Explorer. Gdmfsob! It'll have to go to paintless dent repair, as I don't want it to go to the body shop and get bondo. It's driving me nuts. I hate the person who ruined my new car feeling and caused me so much distress that I end up falling over in the bathroom?

Thank you for ruining the new car. I KNOW WHO DID IT!

20150428

Though I'm not part of the study

I am on extended dosing, and the results are GOOD! There have yet to be any incidents of PML in the extended dosing group!

20150426

The Attack That Changed Me

Ah yes, memories. Of the horrible, nightmarish sort. The kind you want to forget...but you never will.

I'm talking about one of my few episodes of Multiple sclerosis. Its all sort-of fuzzy at this point, as it was certainly not an easy time. I remember having two major episodes before I started a DMT. One of which messed up my vision pretty horribly. I remember trying to go to work, and when I was backing up my nissan pickup, I backed into the wall of the house. Turned my truck off and had my wife drive me to work. I ended up powering through that episode only to have the next one affect me in ways I couldn't fathom. It, my last attack, had changed who I am at the very basic levels of being human. It took from me the ability to make small talk. The basic banter between two people. The kind of talk that doesn't matter, but fills the silent pauses between two people. You don't realize how much small talk squelches those periods of silence until you can't do it anymore. Now my life is filled with awkward silences. I'm getting used to it, but I doubt everyone else has. I like to think I'm fairly adept at hiding my shortcomings. Sort-of tucking them under the rug.

No matter, where was I. Perhaps I was talking about my lack-of-concentration or focus, or I'm not even sure what to call it. I'm starting to feel like a burn-out. I can't hold onto my thoughts anymore. I'll remember I have to get something from the garage and when I walk into the garage I forgot what specific item for which I've gone into the garage. This isn't fun, and I'm getting sick of it. I have yet to find any memory or brain-aid to help with this problem from which I suffer. I don't foresee it getting any better either. This is my new normal. And just like the rest of you, it is ending one day at a time. As long as I don't come down with PML.

But lets end this pity-party on a good note. I'm still up and walking around unassisted. I'm riding my bicycle further and faster than I ever imagined. I'm (at least like to think) still above the mason-dixon line of intelligence. I have two children of which I am still able to care. I have a wife that cares for me and loves me. I am still self-able, for the most part.

20150322

Why is tysabri so scary?

PML and the withdrawl are just the surface.

Here is a partial list from MS-UK

Yes, it is working that well for me.